Precision in Pulsatile GH Release. Ipamorelin stands out in the world of growth hormone research as a synthetic pentapeptide with a unique profile: it is a highly selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). Unlike earlier, broader-acting secretagogues, Ipamorelin is designed to stimulate a natural, pulsatile release of endogenous growth hormone from the pituitary, with minimal off-target effects on cortisol, prolactin, or ACTH. For endocrinologists and metabolic researchers, it provides a cleaner, more specific tool to dissect the GH/IGF-1 axis. 🧬
Imagine a Key That Fits Only the Growth Hormone Release Lock. Ipamorelin's research value lies in its mechanistic elegance and specificity. By mimicking ghrelin's action at the GHSR in the pituitary and hypothalamus, it allows for the study of:
Physiological GH Pulsatility: Enabling research into the benefits of natural, episodic GH spikes versus continuous exposure.
Metabolic & Body Composition Effects: Investigating the role of GH in lipolysis, muscle protein synthesis, and bone metabolism without confounding hormonal fluctuations.
Aging & Sarcopenia Research: Serving as a model for interventions aimed at counteracting age-related decline in GH secretion.
This makes it an ideal candidate for preclinical models focused on metabolic health, fitness recovery, and age-related endocrine decline.
Selective Research Demands Selective Purity. Studying a precise endocrine tool requires a compound of exacting quality.
High Synthetic Purity: ≥98% purity, with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (where Aib is aminoisobutyric acid) confirmed by HPLC and Mass Spectrometry. ✅
Full Analytical Verification: Complete batch-specific Certificate of Analysis (CoA) detailing identity, purity, and content for reproducible scientific outcomes. 📄
Stable & Bioavailable Format: Lyophilized as a stable powder, suitable for subcutaneous administration in chronic in-vivo study protocols. ⚙️
Technical Specifications:
Sequence: H-Aib-His-D-2-Nal-D-Phe-Lys-NH₂
CAS: 170851-70-4
Appearance: White lyophilized powder
Core Research Value: A highly selective GHSR agonist for research into pulsatile growth hormone release and its metabolic effects. 🎯
ZhuoShang Biotechnology Co., Ltd.
Add: Building 2, Chuangzhi 863 Plaza Luolong District Henan China
Tel: +852 63511267
Email: [email protected]